Dedicated to our mission.

Our mission is to advance how the mind is measured to support personalized clinical care across the patient journey.

Pittsburgh, Pennsylvania

About MindTrace

MindTrace was spun out of Carnegie Mellon University to translate advanced techniques in noninvasive and invasive functional brain mapping into structured clinical tools. MindTrace was established to build a scalable platform to meet a long-standing challenge in neurosurgery: how to consistently measure and document neurocognitive function during complex brain procedures.

With support of multiple National Institute of Health (NIH) and National Science Foundation (NSF) Small Business Innovation Research (SBIR) awards, MindTrace has deployed its platform at leading U.S. academic medical centers under Institutional Review Board (IRB) oversight.

As MindTrace transitions from research-driven deployment to broader clinical adoption, the company remains focused on rigorous science, regulatory alignment, and long-term partnerships with clinicians and institutions committed to advancing functional neurosurgery.

Standardizing Functional Assessment in Neurosurgery

1.  Across the Surgical Care Journey

Patients undergoing neurosurgery face meaningful risk to language, memory, attention, and executive function. MindTrace supports structured neurocognitive assessment before, during, and after surgery, enabling consistent documentation across clinical settings and timepoints.

2.  Addressing Variability in Current Practice

Approaches to intraoperative neurocognitive assessment vary across institutions and are often dependent on individual clinician workflow. MindTrace provides a structured framework to support more consistent administration, documentation, and longitudinal tracking of neurocognitive performance.

3.  Aligning Functional Data with Clinical Context

MindTrace enables neurocognitive performance to be reviewed in relation to surgical and neurophysiological events. This alignment supports clearer documentation, interdisciplinary communication, and multi-site reproducibility.

4.  Supporting Patient-Centered Care

By reinforcing structured measurement and documentation, MindTrace supports informed discussions focused on safety, recovery, and quality of life. All medical decision-making remains with the clinical team.

Awards and Recognitions

Programs

MindTrace in Recent Media

Article

Neurosurgeons Are Really Good at Removing Brain Tumors, and They’re About To Get Even Better

In a leap for personalized medicine, CMU scientists have discovered a simple and valuable way to improve brain cancer surgeries. When removing cancerous tissue in the brain, neurosurgeons often use “awake brain mapping” to minimize the risk of causing unintended disruptions to a patient’s quality of life while removing as much tumor as possible. This practice, which has been used for decades, involves waking a patient up mid-surgery to test their neurocognitive functions in real time by stimulating the brain surface and assessing for functional changes.

Media

A Smarter Map for the Brain: Surgeons Pioneer Next-Generation Navigation

The University of Rochester Medical Center (URMC) has begun using a new surgical decision-support technology called MindTrace, marking a significant advance in how brain surgeons plan and perform complex tumor operations. Developed from decades of neuroscience and neurosurgical research, MindTrace helps surgical teams predict how different surgical approaches might affect speech, movement, and other vital functions, helping preserve quality of life after surgery.

Media

Which new startups will bring the next generation of technology to life

Early this year, Richard King Mellon Foundation announced funding for 16 startups, investing a total of $3.39 million in winners of its pitch competition. We wanted to spotlight a small sampling of those companies and the new technologies they’re bringing to life.